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JNK Antibody, HRP

Catalog # Pack Size Price(USD)
ICP6031 100 μg $375.00

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Product Description
These antibodies were tested with human and mouse cell lysates and mouse tissue (brain) extracts to detect Jun NH2-terminal kinases (JNKs). JNK has a molecular weight ranging from 38-56 kDa, which is masked up by the IP IgG bands. Tests using the HRP conjugated anti-JNK do not require secondary Ab, eliminating interference from IgG bands.
 
Western blot analysis of mouse brain extract with ICP6030
A: Extract from control hypoxia mouse brain
B: Extract from control mouse
Species
Rabbit
Formulation
250 µg/mL in HRP stabilizing buffer with 50% glycerol
Immunogen
Human JNK1 (acetylated KLH conjugates)
Purification
The antibody was purified by peptide-affinity chromatography.
Conjugation
Reductive amination; HRP/Ab molar ratio - 10:1
Specificity
The recognition sequence in human and mouse is identical to JNK3, JNK2, and JNK1.
Applications
ELISA (1:1000); WB (1:1000)
Scientific Description
Jun NH2-terminal kinase (JNK) is a member of the mitogen-activatedprotein kinase family, which plays a central role in the regulationof cellular differentiation and proliferation. It also participatesin the regulation of IL-2 and IL-2 receptor gene expression. Over-activation of the c-JNK induces cell death.
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is three years from date of shipping if stored properly.
Product Specific References