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Stat5 Antibody

Catalog # Pack Size Price(USD)
ICP6020 100 µg $295.00

Quantity:

Product Description
Stat5 antibody was developed using a short peptide based on human Stat5. The antibodies were tested against human and mouse cell lysate and mouse tissue (spleen) extract to detect Stat5.
 
Western blot analysis of the extract from mouse spleen ICP0620.
  1. A: Spleen from control             mouse
  2. B: Spleen from mouse             treated with LPS
Species
Rabbit
Formulation
250 µg/mL in PBS, pH7 with 50% glycerol
Immunogen
Human Stat5 peptide (690-712 aa) KLH conjugates
Purification
Affinity purified chromatography
Specificity
The antibody recognizes Stat5 from human and mouse.
Applications
ELISA (1:2500); WB (1:2500); IHC (1:100)
Scientific Description
STAT1 and STAT2 were the first two STAT (signal transducers and activators of transcription) proteins discovered.  They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction.  Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6.[1]  Specific functions of the STAT proteins are poorly understood.  They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

Product Specific References

1. Cell, 1996. 84(3): 331-334. doi:10.1016/S0092-8674(00)81277-5

2. Eur. J. Biochem. 1997. 248(3): 615-633, doi:10.1111/j.1432-1033.1997.00615.x