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p90 RSK1 Antibody

Catalog # Pack Size Price(USD)
ICP9918 100 µg $295.00

Quantity:

Product Description
Affinity purified rabbit polyclonal p90 RSK1 is developed with the C-terminal peptide based on human p90 RSK (C-LAQRRVRKLPSTTL).
 
Western blot analysis of p90 RSK1 immunoprecipitated from  mouse brain extract (B) and using RSK1-HRP as a probe. Immunoprecipitated negative control (A).
Species
Rabbit
Formulation
250 µg/mL in PBS, 50% glycerol, and 0.01% NaN3
Immunogen
Human p90 RSK1 C-terminal peptide (C-LAQRRVRKLPSTTL) KLH conjugates
Purification
The antibody was affinity purified with peptide (C-ISKRPEHLRMNL) KLH on agarose.
Specificity
The antibody recognizes p90 RSK1 of human, mouse and rat.
Applications
ELISA; WB; IP
Scientific Description
p70 S6K is a protein serine/threonine kinase that exists ubiquitously. [1] p70 S6K affects the activities of the cell cycle. One of the members of a family of 90kDa ribosomal protein S6 kinases is called Rsk1. It is activated in response to mitogenic stimuli such as extracellular signal regulated protein kinases Erk1 and Erk2. Rsk1 is activated by MAPK in vitro and in vivo via phosphorylation. It plays an important role in transcriptional regulation.
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is one year from date of shipping if stored properly.

Product Specific References

  1. 1. Curr. Biol. 1999. 9(15): 810-820. doi: 10.1016/S096-9822(99)80364-9