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MEK 1/2 Antibody

Catalog # Pack Size Price(USD)
LAN2010 100 μg $295.00

Quantity:

Product Description
This antibody was developed and affinity purified using a peptide based on human MEK1. This antibody was tested to be able to detect both human MEK1 and MEK2 using human cell lysates.
 
Representative western blot with anti-MEK1/2 (1:1000) using,  from left to right, 10 µg, 20 µg and 40 µg of 293 cell lysate.
Species
Rabbit
Formulation
1000 µg/mL in TBS with 50% glycerol
Immunogen
MEK1 peptide (210-255 aa) KLH conjugates
Protein code: Q02750
Purification
Affinity specific affinity chromatography
Specificity
Recognizes both MEK1 and MEK 2 , human and mouse
Applications
ELISA  (>1:2000); WB (>1:1000); IP (5 µg/mg protein)
Scientific Description
MEK1 is a member of the dual specificity protein kinase family that acts as a mitogen-activated protein kinase (MAPK) kinase. MEK1 lies upstream of MAPK/ERK and stimulates the enzymatic activity of MAPK/ERK upon a wide variety of extra- and intracellular signals. As an essential component of MAPK/ERK signal transduction pathway, MEK1 is involved in many cellular processes such as proliferation, differentiation, transcription regulation and development.
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage,  store product at -20°C. Expiration date is three years from date of shipping if stored properly.