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NG,NG-dimethyl Arginine Antibody (anti-dMeR), HRP

Catalog # Pack Size Price(USD)
ICP0812 100 µg $375.00


Product Description
This antibody is raised from rabbits that were immunized with NG,NG-dimethyl arginine-KLH conjugates and specifically isolated and affinity purified using the NG,NG-dimethyl arginine antigen. The affinity purified methyl arginine antibody is useful for detection, isolation and localization of proteins with methylated arginine (asymmetric dimethylation) residues.
Antigen Structure
250 µg/mL in stabilizing buffer with 50% glycerol
N5,NG-dimethyl arginine-KLH conjugates
Aldehyde-activated HRP via reductive amination
HRP/Ab ratio: 3:1
The antibody recognizes proteins with dimethylated arginine residues. It does not cross react with acetylated proteins or mono-methylated proteins.
Species Tested
Human, mouse and pig
ELISA (1:2000); WB (1:1000); IP (5 µg/mg protein sample); IF (5 µg/mL); IHC (5 µg/mL)
Scientific Description
Arginine methylation is a very common post-translational modification that occurs predominantly in the nucleus. The main pool of proteins that are modified in such a way possess RNA binding properties. More broadly, arginine methylation has been implicated in a variety of cellular processes including protein trafficking, signal transduction and transcriptional regulation.  
Storage & Stability
Product is stable for several weeks at 4°C. For extended storage, store product at -20°C. Expiration date is six months from date of shipping if stored properly.
Product Specific References
1. Mol Microbiol. 2007. 65: 590-606. doi:10.1111/j.1365-2958.2007.05831.x