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Anti-Akt (phospho ser473), HRP Conjugates (ICP0455) |
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Pack Size |
Price (US) |
| ICP0455-100 |
100ug |
$280.00 |
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Description: AKT (PKB) is a family kinase, which is responsive to the cell activation. The anti-Akt phosphor ser473 antibodies were raised with an antigen peptide based on sequence of human Akt1 C-terminal with the phosphor-site at ser473 and affinity purified with the same peptide followed by adsorption with the non-phospho peptide on the agarose. The affinity purified antibodies were useful for detection of the Akt kinase with phosphorylation site at ser473 only, not cross-react with the non-phosphorylated Akt. |
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Species: Rabbit
Formulation: 250 µg/mL in PBS, 50% glycerol
Storage & Stability: Store product at –20 0C. One year from date of shipping
Immunogen: Phosphorylated prptide (ser473) based Human Akt c-terminal sequence.
Purification: Antigen-specific chromatography plus non-specific adsorption
Application(s): ELISA, Westernblot, IHC
Specificity: Recognize phosphorylated Akt on serine 473. There is no cross-reaction with the non-phosphorylated Akt
Scientific Description: Akt is also known as protein kinase B (PKB). It is an important molecule in mammalian cellular signaling. It inhibits apoptotic processes and is involved in cellular survival pathways. It also induces protein synthesis pathways
Reference: Garofalo, R. S. at al. Journal of Clinical Investigation 2003, 112, 197-208.
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