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Anti-Stat1 (ICP6010) |
| Catalog Number |
Pack Size |
Price (US) |
| ICP6010-100 |
100µg |
$250 |
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Description: The Stat1 transcription factor is activated in response to a large number of ligands and is essential for responsiveness to IFN-α and IFN-γ . This antibodies were raised based on the human Stat1 sequnce (690-720 aa) and tested in westernblotting of human and mouse cell lysate and mouse tissue (spleen) extract to detect the Stat1.
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Species: Rabbit
Formulation: 250 µg/mL in PBS, pH7 with 50% Glycerol.
Storage & Stability: Store product at –20 0C. Three years from date of shipping.
Immunogen: Human Stat1 peptide KLH conjugates
Purification: Peptide-affinity chromatography.
Specificity: Recognize stat1, human, mouse.
Application(s): ELISA, WB, immunohistochemistry.
Scientific Description: STAT1 and STAT2 were the first two STATs (signal transducers and activators of transcription) proteins discovered. They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction. Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6. [1] Specific functions of the STAT proteins are poorly understood. They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
References: 1. Cell, 84: 331-334, 1996.
2. Eur. J. Biochem., 248: 615-633, 1997.
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