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Anti-Stat3 (ICP6015) |
| Catalog Number |
Pack Size |
Price (US) |
| ICP6015-100 |
100µg |
$250 |
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Description: Stat3 antibody was developed using short peptide based on human stat3 sequence.
The antibodies were test against human cell and mouse tissues extract (spleen) to detect the Stat3 in western blot. Immunohistochemistry was tested using human breast cancer tissue.
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Western blot : Western blot analysis of the extract from mouse spleen and human lump using ICP6015 with (A) and without competitive antigen peptide (B).
Species: Rabbit
Formulation: 250 µg/mL in PBS, pH7 with 50% Glycerol.
Storage & Stability: Store product at –20 0C. Three years from date of shipping.
Immunogen: human Stat3 peptide (720-732 aa) KLH conjugates.
Purification: Peptide-affinity chromatography.
Specificity: The antibody recognizes Stat3 in mouse and Human.
Application(s): ELISA, 1: 2500, WB, 1:2500, Immunohistochemistry, 1:100.
Tested: Mouse, Human
Scientific Description: STAT1 and STAT2 were the first two STATs (signal transducers and activators of transcription) proteins discovered. They are involved in interferon-alpha (IFN-alpha) and IFN-gamma signal transduction. Other STAT proteins that have been identified are STAT3, 4, 5a, 5b, and 6. [1] Specific functions of the STAT proteins are poorly understood. They are thought to be involved in a variety of systems including antiviral responses and cell transformation. [2]
References: 1. Cell, 84: 331-334, 1996.
2. Eur. J. Biochem., 248: 615-633, 1997.
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