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Anti-p53 (ICP7110) |
| Catalog Number |
Pack Size |
Price (US) |
| ICP7110-100 |
100µg |
$250 |
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Description: These antibodies were developed based on human p53 sequence (25-40 aa). It was tested to detect the human p53 in human cell and tissue.
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Species: Rabbit
Formulation: 1000 µg/mL in PBS, pH7 with 50% glycerol
Storage & Stability: Store product at –20 0C. One year from date of shipping.
Immunogen: Human phosphor p53 peptide (15-40aa) KLH conjugates
Purification: Peptide-affinity chromatography
Application(s): ELISA, 1: 2500, WB, 1:2500
Specificity: The antibody recognizes human p53 in cell and tissue.
Western blot : Western blot analysis of the p53 in Hela cell lysates with anti-p53 (ICP7110)
A: 15 ug/mL crude protein
B: 45ug/mL crude protein
Scientific Description: p53 (tumor protein 53 or TP53) regulates cell cycle by acting as a transcription factor. It suppresses tumor and hence it is often described as "the guardian of the genome", "the guardian angel gene", or the "master watchman". This is referred to its role in conserving stability by preventing genome mutation.[1] p53 is referred to its molecular mass (53 kDa)) protein on SDS-PAGE.
References: Strachan T. et al. Human Molecular Genetics 2. Ch. 18, 1999 Cancer Genetics.
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